Marie Skepö, Professor
Grant for PRISMAS PhD-student. Autumn 2022
Marie Skepö (PI), in collaboration with the CoSAXS-team at MAX IV and Astra Zeneca in Gothenburg have obtained a grant through PRISMAS, which is a – PhD Research and Innovation in Synchrotron Methods and Applications in Sweden – is a new doctoral programme training the next generation of leading synchrotron experts. The PRISMAS program has received funding from the European Union’s COFUND action, a part of the Marie Skłodowska-Curie Actions Program within the European Commission MSCA framework. Expected announcement of the position is spring 2023, and the project will focus on liquid-liquid phase separation mediated by phosphorylated intrinsically disordered proteins utilizing computer simulations in combination with SAXS. Besides conventional SAXS measurements or sample environments, addition of instrumentation as stopped-flow devices could bring new information to the study. For more information, please see: https://www.maxiv.lu.se/education-outreach/programs-and-activities/prismas/. PRISMAS includes an on-site secondment at the large-scale research facility and synchrotron MAX IV in Lund, Sweden.
Grant for WISE-post doc in material science. Autumn 2022
Marie Skepö (PI) in collaboration with Daniel Topgaard, and Leif Bulow, has received a postdoc in material science through the Wallenberg Initiative Materials Science for Sustainability (WISE, wise-materials.org). WISE, funded by the Knut and Alice Wallenberg Foundation, is the largest-ever investment in materials science in Sweden and will encompass major efforts at Sweden’s foremost universities over the course of 10 years. The vision is a sustainable future through materials science. Read more: https://wise-materials.org. The project is about using clay as a green fertilizer, and for this study we aim to use computer simulations in combination with NMR, SAXS, and osmotic stress measurements.
Grant for Neutron Research awarded by NordForsk
Marie Skepö (PI), has in collaboration with Lise Arleth and Kresten Lindorff-Larsen at University of Copenhagen, and Jens Preben Morth at University of Oslo, been awarded 6.8 MNOK for studying the structure of membrane proteins under solution conditions. The aim is to understand how the lipid environment influences the activity of membrane proteins, using the active transporter MgtA as benchmark system, and to investigate the dynamic fluctuations between lipid and protein in solution, utilising neutron and X-ray scattering in combination with computer simulations.
Research projects
- To reveal static and dynamic properties of intrinsically disordered proteins (IDPs) to provide a deeper understanding of the mechanism of action and the static as well as dynamic structure-function relationship.
- Establish a quantitative link between polymer theory, computer simulations, and experiments, predominantly scattering, for IDPs.
- Pushing the boundaries regarding analyzing scattering data with computer simulations.
- Structural and thermodynamical properties of colloids with focus on anisotropic particles (clay).
Academic background
- Member of Pedagogiska Akademin (excellent teaching practitioner) at Faculty of Science, Lund University, 2014
- Associate Professor in Theoretical Chemistry, Lund University, 2014
- Docent in Theoretical Chemistry, Lund University, 2014
- Assistant Professor in Theoretical Chemistry, Lund University, 2010-2014. Financed by Vinnova and Faculty of Science
- Researcher at Health and Society, Biofilm project, Malmö University, 2003-2008
- PhD in Physical Chemistry, Lund University, 2002
- University Diploma in Education for Upper Secondary School, Subjects Mathematics and Chemistry, Växjö University, 1998
- Bachelor of Science, in Chemistry, Växjö University, 1997
- University Certificate in Chemical Engineering, Växjö University, 1994
Publications
Please follow links to Google Scholar or Research Gate for full publication list.
