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Amanda Eriksson Skog, PhD student


Antibiotics are widely used all over the world to treat infections caused by bacteria. However, the past centuries overuse of it has caused an increasing resistance against antibiotics in bacteria. Therefore, alternative ways to treat bacterial infections is needed. Antimicrobial peptides could be the answer to this problem. They are a natural part of our immune system, and development of resistance against them seem to be rather low. These peptides are however quite quickly degraded by the body, as well as could be quite toxic. Hence, ways to transport these peptides to where they should act is needed, both to prevent them from being degraded, as well as protect the body from the toxicity, as well as fully understand their way of action to improve their function.


In my research I study the behavior of the intrinsically disordered multifunctional saliva peptide Histatin 5, shown to have both antifungal as well as antibacterial effects, when exposed to a lipid membrane.Through various scattering and surface adsorption techniques the lipid-peptide interactionis investigated, trying to understand the underlying mechanism of the interaction. The project is in collaboration with Dr. Yuri Gerelli at Polytechnic University of Marche, Ancona, Italy.


+46 222 82 39
amanda[dot] eriksson_skog [at] compchem [dot] lu [dot] se